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Takao Saruta Selected Research

Calcium Channel Blockers (Blockers, Calcium Channel)

1/2020Effects of an Antihypertensive Combination in Japanese Hypertensive Outpatients Based on the Long-acting Calcium Channel Blocker Benidipine on Vascular and Renal Events: A Sub-analysis of the COPE Trial
1/2018Effects of Calcium-Channel Blocker Benidipine-Based Combination Therapy on Cardiac Events　- Subanalysis of the COPE Trial.
1/2016Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial.
10/2015Preferable effects of olmesartan/calcium channel blocker to olmesartan/diuretic on blood pressure variability in very elderly hypertension: COLM study subanalysis.
1/2015Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial.
4/2012Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial.
8/2011Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial.
6/2011How to use marginal structural models in randomized trials to estimate the natural direct and indirect effects of therapies mediated by causal intermediates.
1/2011Effect of antihypertensive treatment on cardiovascular events in elderly hypertensive patients: Japan's Benidipine Research on Antihypertensive Effects in the Elderly (J-BRAVE).
5/2010Effects of combination olmesartan medoxomil plus azelnidipine versus monotherapy with either agent on 24-hour ambulatory blood pressure and pulse rate in Japanese patients with essential hypertension: additional results from the REZALT study.
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Takao Saruta Research Topics

Disease

36Hypertension (High Blood Pressure)
01/2020 - 08/2002
14Proteinuria
01/2010 - 04/2001
14Insulin Resistance
09/2009 - 05/2002
14Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2008 - 04/2002
13Stroke (Strokes)
01/2020 - 04/2001
12Essential Hypertension
07/2014 - 11/2002
10Type 2 Diabetes Mellitus (MODY)
07/2014 - 03/2002
9Chronic Renal Insufficiency
11/2013 - 07/2003
9Diabetic Nephropathies (Diabetic Nephropathy)
01/2010 - 01/2003
7Fibrosis (Cirrhosis)
01/2006 - 10/2002
6Cardiovascular Diseases (Cardiovascular Disease)
01/2018 - 03/2004
6Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2011 - 11/2002
6Obesity
06/2010 - 08/2002
5Autoimmune Diseases (Autoimmune Disease)
12/2005 - 07/2003
4Neoplasms (Cancer)
07/2006 - 01/2003
4Glomerulonephritis
04/2005 - 09/2002
4Body Weight (Weight, Body)
12/2004 - 05/2003
3Isolated Systolic Hypertension
01/2017 - 09/2004
3Renal Insufficiency (Renal Failure)
11/2013 - 12/2001
3Adenoma (Adenomas)
06/2011 - 01/2003
3Heart Failure
01/2011 - 09/2003
3Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2010 - 09/2004
3Kidney Diseases (Kidney Disease)
02/2007 - 12/2004
3Hyperglycemia
06/2006 - 01/2004
3Vascular System Injuries
04/2005 - 12/2003
3Coronary Artery Disease (Coronary Atherosclerosis)
07/2004 - 08/2002
3AIDS-Related Complex (ARC)
11/2003 - 02/2002
3Ischemia
09/2002 - 05/2002
2Sepsis (Septicemia)
11/2013 - 10/2000
2Infections
11/2013 - 06/2006
2Diabetes Mellitus
11/2013 - 02/2010
2Myocardial Infarction
01/2011 - 12/2003
2Edema (Dropsy)
05/2008 - 11/2004
2Hyperuricemia
02/2008 - 08/2007
2Hypokalemia
08/2007 - 01/2000
2Vascular Remodeling
07/2006 - 04/2005
2Atherosclerosis
07/2006 - 11/2004
2Hyperkalemia
04/2006 - 02/2003
2Acute Kidney Injury (Acute Renal Failure)
10/2005 - 12/2003
2Chronic Kidney Failure (Chronic Renal Failure)
02/2005 - 10/2003

Drug/Important Bio-Agent (IBA)

21Angiotensin Receptor AntagonistsIBA
01/2018 - 04/2001
17Antihypertensive Agents (Antihypertensives)IBA
01/2016 - 09/2004
16Calcium Channel Blockers (Blockers, Calcium Channel)IBA
01/2020 - 04/2004
14candesartanIBA
01/2011 - 10/2002
13Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2006 - 04/2001
12Insulin (Novolin)FDA Link
11/2007 - 04/2002
9benidipineIBA
01/2020 - 01/2011
9Amlodipine (Norvasc)FDA LinkGeneric
02/2012 - 05/2006
8AldosteroneIBA
03/2010 - 11/2002
8Proteins (Proteins, Gene)FDA Link
01/2005 - 08/2002
7Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA
01/2018 - 04/2005
7ReninIBA
01/2010 - 04/2001
7Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
06/2006 - 11/2002
7LipidsIBA
03/2005 - 08/2002
7Glucose (Dextrose)FDA LinkGeneric
03/2005 - 10/2002
6AngiotensinsIBA
01/2010 - 04/2001
6Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2007 - 05/2002
6Angiotensin IIIBA
01/2007 - 04/2001
6SaltsIBA
01/2007 - 08/2002
5ThiazidesIBA
01/2020 - 04/2012
51,4-dihydropyridine (dihydropyridine)IBA
01/2018 - 12/2009
5Valsartan (Vals)FDA Link
01/2017 - 09/2004
5DiureticsIBA
10/2015 - 04/2004
5Nifedipine (Adalat)FDA LinkGeneric
07/2008 - 03/2004
5rho-Associated KinasesIBA
01/2006 - 12/2003
5AdiponectinIBA
07/2004 - 03/2002
4CalciumIBA
11/2013 - 07/2003
4Pharmaceutical PreparationsIBA
11/2013 - 05/2004
4Hydrocortisone (Cortisol)FDA LinkGeneric
06/2011 - 01/2003
4EnzymesIBA
06/2011 - 01/2003
4efonidipineIBA
11/2010 - 02/2003
4PPAR gammaIBA
05/2008 - 05/2002
4Vasodilator Agents (Vasodilators)IBA
01/2008 - 04/2001
4Spironolactone (Aldactone)FDA LinkGeneric
04/2006 - 11/2002
4ChemokinesIBA
02/2006 - 11/2003
4AutoantibodiesIBA
11/2003 - 04/2002
3olmesartanIBA
10/2015 - 10/2014
3Collagen Type IV (Type IV Collagen)IBA
01/2010 - 09/2003
3CreatinineIBA
08/2009 - 11/2003
3LigandsIBA
05/2008 - 05/2002
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2008 - 05/2002
3Pioglitazone (Actos)FDA Link
05/2008 - 03/2002
3Angiotensin II Type 1 Receptor BlockersIBA
02/2008 - 09/2002
3Eplerenone (Inspra)FDA LinkGeneric
04/2006 - 04/2004
3Hormones (Hormone)IBA
10/2004 - 03/2002
3candesartan cilexetil (Amias)FDA Link
11/2003 - 04/2001
2azelnidipineIBA
05/2010 - 12/2009
2Olmesartan Medoxomil (Votum)FDA Link
05/2010 - 12/2009
2Matrix Metalloproteinases (MMPs)IBA
01/2010 - 08/2009
2Streptozocin (Streptozotocin)FDA Link
10/2008 - 06/2003
2Uric Acid (Urate)IBA
02/2008 - 08/2002
2Losartan (Cozaar)FDA LinkGeneric
08/2007 - 11/2003
2A-factor (Streptomyces)IBA
02/2007 - 04/2004
2NF-kappa B (NF-kB)IBA
08/2005 - 02/2003
2Mineralocorticoid Receptor AntagonistsIBA
01/2005 - 12/2004
2trandolapril (Mavik)FDA LinkGeneric
01/2005 - 11/2003

Therapy/Procedure

26Therapeutics
01/2020 - 01/2003
3Renal Dialysis (Hemodialysis)
06/2006 - 05/2005
2Hemodiafiltration
11/2013 - 10/2005
2Nephrectomy
01/2006 - 01/2005